Thursday, November 5, 2009

“New discoveries in the yeast Saccharomyces cerevisiae - Eureka! Science News” plus 4 more

“New discoveries in the yeast Saccharomyces cerevisiae - Eureka! Science News” plus 4 more


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New discoveries in the yeast Saccharomyces cerevisiae - Eureka! Science News

Posted: 05 Nov 2009 05:50 AM PST

The study, entitled 'Moonlighting Proteins HAL3 and VHS3 Form a Heteromeric PPCDC with YKL088w in Yeast CoA Biosynthesis' and published in Nature Chemical Biology, was carried out by researchers of the UAB Department of Biochemistry and Molecular Biology and the University of Stellenbosch, South Africa, under the coordination of Dr Joaquin Arino...

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More Bay Area News - San Francisco Chronicle

Posted: 05 Nov 2009 06:05 AM PST

The government-funded venture will encourage the scientists working toward varied goals to share their research and collaborate with others using different approaches.

The Gladstone-Stanford team is seeking to develop pluripotent stem cells, which are artificially derived from ordinary human tissue specifically for the purpose of repairing cells in damaged heart muscle.

Other Stanford scientists have teamed up with researchers at Johns Hopkins University in Baltimore to learn how to reprogram the genes of adult stem cells into lines of specialized cells that could treat disorders of the blood and blood vessels.

Deepak Srivastava, director of the Gladstone Institute of Cardiovascular Disease, and Robert Robbins, Stanford chairman of cardiothoracic surgery, head one joint heart disease team, while John Cooke, Stanford professor of cardiovascular medicine, is working with Alan Friedman, a pediatric cancer specialist at Johns Hopkins.

With $170 million in grants from the National Heart, Lung and Blood Institute, other stem cell research teams are being linked at the Universities of Wisconsin and Minnesota; at the Children's Hospital of Philadelphia and the Fred Hutchinson Cancer Center in Seattle; at the University of Texas in Dallas and the Massachusetts General Hospital in Boston; and at Boston's Children's Hospital and Massachusetts General Hospital.

In addition, a unique venture at Stanford links biochemistry professor Mark Krasnow with Irving Weissman, director of Stanford's Institute for Stem Cell Biology and Regenerative Medicine, to study progenitor cells in blood and lung tissue for possible future therapies.

Progenitor cells are, in a sense, the progeny of both adult and embryonic stem cells; they can divide only a limited number of times and transform into a limited number of tissue cell types.

The research teams are being linked by the federal heart and blood institute into a Progenitor Cell Biology Consortium and the scientists have already met in the first of a series of sessions over the next seven years to exchange reports on their research progress.

"This is an important effort to break down the barriers that have kept so many research groups working apart," said Srivastava, who is directing the Gladstone heart work. "It will enable scientists in all the research groups to interact much more deeply."

"If we bring people together from different research areas maybe we can speed the progress up a bit," said Weissman. "We're just trying to stir the pot, and it's needed."

E-mail David Perlman at dperlman@sfchronicle.com.

This article appeared on page C - 2 of the San Francisco Chronicle

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New Initiatives To Bolster Science And Technology Collaboration With ... - Redorbit.com

Posted: 05 Nov 2009 07:16 AM PST

Posted on: Thursday, 5 November 2009, 09:20 CST

In remarks at the Forum for the Future in Marrakech yesterday, Secretary Clinton announced new initiatives to bolster science and technology collaboration with Muslim communities around the world. The Secretary named Dr. Bruce Alberts, Dr. Elias Zerhouni, and Dr. Ahmed Zewail as the first three U.S. Science and Technology Envoys and announced that the State Department will expand positions for environment, science, technology, and health officers at U.S. embassies.

"We want to help Muslim majority communities develop the capacity to meet economic, social and ecological challenges through science, technology, and innovation," Secretary Clinton said.

The U.S. Science Envoy program is part of President Obama's "New Beginning" initiative with Muslim communities around the world that he launched in a June 4 speech in Cairo, Egypt. He pledged that the United States would "appoint new science envoys to collaborate on programs that develop new sources of energy, create green jobs, digitize records, clean water, and grow new crops." The initiative received key support from the Senate Foreign Relations Committee and Senator Richard Lugar.

In the coming months, the first Science Envoys will travel to countries in North Africa, the Middle East, and South and Southeast Asia. They will engage their counterparts, deepen partnerships in all areas of science and technology, and foster meaningful collaboration to meet the greatest challenges facing the world today in health, energy, the environment, as well as in water and resource management. Additional U.S. scientists and engineers will be invited to join the Science Envoy program to expand it to other Muslim countries and regions of the globe.

Dr. Bruce Alberts is widely recognized for his work in the fields of biochemistry and molecular biology. Dr. Alberts is a professor in the Department of Biochemistry and Biophysics at the University of California, San Francisco. As president of the National Academy of Sciences (NAS) from 1993 to 2005, he was instrumental in developing the landmark National Science Education standards that have been implemented in school systems throughout the U.S.

Dr. Elias Zerhouni, M.D., was director of the National Institutes of Health (NIH) from 2002 to 2008. Dr. Zerhouni is currently a senior advisor to Johns Hopkins University School of Medicine and was instrumental in creating the University's Institute for Cell Engineering. Dr. Zerhouni received his medical degree at the University of Algiers School of Medicine and completed his residency at the John Hopkins School of Medicine.

Dr. Ahmed Zewail is the Linus Pauling Chair Professor of Chemistry and Professor of Physics at the California Institute of Technology and Director of the Institute's Physical Biology Center for Ultrafast Science and Technology. Dr. Zewail was awarded the Nobel Prize in Chemistry in 1999 for his pioneering work in femtoscience, which allowed observation of exceedingly rapid molecular transformations. Most recently, Dr. Zewail was appointed to the Presidential Council of Advisors on Science and Technology.

The envoys will be supported by new embassy officers who will also engage with international partners on the full range of environmental, scientific and health issues, from climate change and the protection of oceans and wildlife to cooperation on satellites and global positioning systems. They will work with multilateral institutions, non-governmental organizations and private sector partners to promote responsible environmental governance, foster innovation, and increase public engagement on shared environmental and health challenges.

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Soil samples to help save Potter Lake - KTKA

Posted: 05 Nov 2009 06:33 AM PST

— Kansas University scientists who travel all over the state gathering data on lakes stayed home on Wednesday conducting research in their backyard.

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Jerry deNoyelles, deputy director of the Kansas Biological Survey and a professor in the ecology and evolutionary biology department at Kansas University, disassembles a coring unit after taking a core sample from Potter Lake Wednesday, Nov. 4, 2009 at Potter Lake. Both Kansas Biological Survey officials and Kansas University faculty from both the ecology and evolutionary biology department and the environmental studies department worked to extract core samples from the lake to measure sedimentation. In back are KU environmental studies professor Bob Hagen and Lenexa senior Ryan Callihan.

What they found was enough silt in Potter Lake to fill roughly 600 dump trucks with mud.

A group from the Kansas Biological Survey took soil samples at Potter Lake to determine how much it would cost to dredge the aging pond.

"That's an awful lot of silt, considering we have a fairly small watershed here," said Mark Jakubauskas, a research associate professor at the Kansas Biological Survey.

A campus treasure, Potter Lake once hosted canoe races and had diving platforms. In the 1950s, it was drained and dredged. Over the past half century, runoff has washed into the lake, filling it with sediment, nutrients and plant life.

This summer, the lake's health was at a crisis point. Heavy rainfalls led to a burst in plant growth, which sucked oxygen from the water. As a result, hundreds of fish died.

This fall, student groups joined together to make improvements — scooping out 8 tons of coontail one pitchfork at a time. They also added aerators to increase the lake's oxygen levels.

It's time to dredge the lake again, said Jerry deNoyelles, deputy director of the Kansas Biological Survey.

"It is probably the only long-term solution that there is," he said.

It was a solution that had the scientists building a wooden ramp Wednesday to launch a 24-foot pontoon boat into the one-and-a-half-acre lake.

"We're in. We are not coming out," deNoyelles joked as the boat glided into the water.

By using a 15-foot drilling rig called a vibracore — a kind of giant metal straw with a motor on top — the scientists were able to push through the silt to reach the original bottom of the lake and then pull the sediment up in a tube.

More than a half-dozen of these core sediment samples were taken. By noon, the group had enough data to estimate the lake had an average of two feet of sediment on the bottom — a total of 5,000 cubic yards of silt.

Previous student groups have estimated it would cost between $50,000 and $100,000 to dredge the lake.

Along with helping establish the cost of dredging, Wednesday's sediment collection will be sent to labs to be analyzed. That information will help determine what dredging methods will work best.

And, just in case any former KU students were wondering, the group hadn't come across any lost car keys, term papers or textbooks. So far, the scientists have pulled up only mud.

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Lab offers ‘think tank’ of ideas - Appalachian Online

Posted: 05 Nov 2009 08:21 AM PST

by NASH DUNN
News Reporter

Appalachian State University's Department of Health, Leisure and Exercise Science (HLES) opened a new Vascular Biology and Autonomic Laboratory Oct. 15 in partnership with the Institute of Health and Human Services (IHHS).

The laboratory, on the second floor of University Hall located behind Staples, is a "satellite lab," and will house vascular and autonomic studies in addition to multi-disciplinary research.

The Departments of Chemistry, Nutrition, Health Promotion, Psychology and Family and Consumer Sciences have already shown interest in conducting collaborative research in the lab.

"It's a meeting place for ideas, and almost a think tank," HLES professor Scott Collier said. "It's an incredible opportunity to be multi-disciplinary. We have the ability to collaborate now with everybody in the community and on campus."

Paul L. Gaskill, HLES director said the lab benefits HLES' three-pronged mission for scholarship, research and study. 

"It's a teaching lab for graduates and undergraduates, it is a research and scholarship environment where data is collected and analyzed, and it is a service environment because the subjects are benefitted from what we're doing in the lab," Gaskill said.

While the main focus of the lab will be how exercise and exogenous supplements affect blood pressure, studies will also focus on arterial health and how they remodel through different treatments.

"We want to look at vessel health and by looking at that we can determine a local treatment that would be specific to that person, whether it is exercise prescription, nutrition prescription, psychological prescription or the combination of any of those," Collier said.

The lab is financed by start-up funds, internal grants and donated equipment from HLES and Watauga County Medical Center.

Due to the lack of space and access at the Human Performance Laboratory in Holmes Convocation Center, lab areas for HLES research are in constant need, Collier said. 

When University Hall began its recent renovation, IHHS director John M. Turner met with HLES and reserved a rent-free space for the new lab.

"[Our] testing utilizes a lot of people from the community, and the new facility at University Hall allows for community parking and handicapped access," Collier said.

Collier strongly encourages anyone with research in this area to contact him at This e-mail address is being protected from spam bots, you need JavaScript enabled to view it

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